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February 05, 2007

Physicians do not always practice what drug watchdog preaches

The UK government's drug watchdog NICE has received a lot of publicity recently after publishing guidelines restricting the prescription of certain cognitive enhancers for Alzheimer's disease for reasons of cost. However, a recent survey of 181 neurologists by Datamonitor indicates that the NICE cost-benefit methodology may not reflect how the drug is actually used in the clinical setting.

'Content Cognitive enhancers do not treat the cause of Alzheimer's, rather they seek to prevent the cognitive decline associated with it, and fall into two categories: acetycholinesterase inhibitors (AChEIs) including Aricept (donepezil), Exelon (rivastigmine) and Razadyne (galantamine), or the NMDA antagonist memantine, which is branded as Namenda and Ebixa in the US and Europe respectively.

Source: PBR Staff Writer. Alzheimer's disease: physicians do not always practice what NICE preaches (5 Feb 2007) [FullText]

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