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December 22, 2004
Alzheimer's research is not science, The Scientist article says
Dear Alzheimer's scholar,
You may wonder, what is the major message for Alzheimer's disease research 2004? What is an essential note missing that will arrest future advancement in the coming year? Most of you by now should know the answer.
For those of you who miss the point, please see the Upfront article of the recent issue of The Scientist (6 December 2004, p.6) and a series of this year articles on Alzheimer's in The Wall Street Journal (available at this link).
The Scientist article particularly states with regard to amyloid hypothesis:
"When hypotheses dominate, they take on lives of their own so, that nearly all the research is designed to support the tenets of dogma, and any new data is interpreted in such a way that seeks to buttress the validity of dogma. Science flourished after the enlightenment due to the competition among ideas and multiple hypotheses. If this is not allowed to happen, it is not science."
Don't lie yourself. As a scholar your mission is to serve Alzheimer's patients, not those who forgot about patients and has corrupted Alzheimer's field, Alzheimer's publications, Alzheimer's grant support, and related to Alzheimer's faculty appointments.
Unlike Elan Director Dennis J. Selkoe who lately sold another portion of his Elan shares (by EdgarOnline: 24 Nov 2004, 60,000 shares, $1,690,800 value; For the analysis of previous sale coincided with Alzheimer's patient deterioration in a UK clinic, see UK government publication of 20 July 2004) most of you has little to loose on dropping the amyloid dogma. So, why not to clean up your mind for fresh ideas before New Year comes? Think of it.
Further reading on why tackling amyloid is a waste of time (and a danger to patients) is available in just published article available at this link at ScienceDirect.
To express your thoughts please provide comments by following the link below.
Happy Holiday Season! Happy and Wealthy New Near 2005 to you, Alzheimer's victims and their family members!
Sincerely,
Alexei Koudinov, MD, PhD
You may wonder, what is the major message for Alzheimer's disease research 2004? What is an essential note missing that will arrest future advancement in the coming year? Most of you by now should know the answer.
This message is: Significant portion of Alzheimer's research is not science.
For those of you who miss the point, please see the Upfront article of the recent issue of The Scientist (6 December 2004, p.6) and a series of this year articles on Alzheimer's in The Wall Street Journal (available at this link).
The Scientist article particularly states with regard to amyloid hypothesis:
"When hypotheses dominate, they take on lives of their own so, that nearly all the research is designed to support the tenets of dogma, and any new data is interpreted in such a way that seeks to buttress the validity of dogma. Science flourished after the enlightenment due to the competition among ideas and multiple hypotheses. If this is not allowed to happen, it is not science."
Don't lie yourself. As a scholar your mission is to serve Alzheimer's patients, not those who forgot about patients and has corrupted Alzheimer's field, Alzheimer's publications, Alzheimer's grant support, and related to Alzheimer's faculty appointments.
Unlike Elan Director Dennis J. Selkoe who lately sold another portion of his Elan shares (by EdgarOnline: 24 Nov 2004, 60,000 shares, $1,690,800 value; For the analysis of previous sale coincided with Alzheimer's patient deterioration in a UK clinic, see UK government publication of 20 July 2004) most of you has little to loose on dropping the amyloid dogma. So, why not to clean up your mind for fresh ideas before New Year comes? Think of it.
Further reading on why tackling amyloid is a waste of time (and a danger to patients) is available in just published article available at this link at ScienceDirect.
To express your thoughts please provide comments by following the link below.
Happy Holiday Season! Happy and Wealthy New Near 2005 to you, Alzheimer's victims and their family members!
Sincerely,
Alexei Koudinov, MD, PhD
posted by Dr. Koudinov @ 22.12.04
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