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November 13, 2004

Science news: Research suggests a physiological role for amyloid beta

Jill Adams, "Assessing Amyloid beta. Research suggests a physiological role for the presumed villain" (29 March 2004, Vol. 18(6): p. 25 The Scientist)
Leading text: "Recent work has revealed a potential physiological role for amyloid b, often considered a major culprit in Alzheimer disease (AD) pathology. This suggests that Ab, an ordinarily upstanding protein, turns bad as the result of a mob-type effect, when the physical buildup into plaques promotes neuronal damage and loss. "There's been a growing awareness over the last three or four years that it's not just a toxic peptide," says Hugh Pearson from the University of Leeds, UK..." [FullText]

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