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November 19, 2005
Statins may slow down Alzheimer's
"Cholesterol treatment, including statins, may slow down the progression of Alzheimer's disease, the results of a new study indicate. A team of researchers assessed the degree of brain function loss caused by Alzheimer's disease in 342 patients attending a memory clinic. The progress of the disease among the group was then monitored for a further three years. The average age of the patients was 73. Altogether, 129 of the participants had abnormal cholesterol levels, almost half of whom were being treated exclusively with statins. Statins are a group of drugs used in the treatment of people with high cholesterol levels. A further 105 of the participants had abnormal but untreated cholesterol. The remaining 108 participants had normal cholesterol levels.
The researchers found that during the three years, all of the patients deteriorated as a result of Alzheimer's. However the disease progressed significantly slower in the patients who were being treated for abnormal cholesterol levels. In fact, progression of the disease was rated at 1.5 points a year in those given cholesterol drugs, 2.4 in those whose cholesterol was untreated and 2.6 in those with normal cholesterol levels. The research team concluded that cholesterol lowering drugs effectively slow down the progression of the disease. However they emphasised that a larger study would be required to confirm these findings. Details of this study are published in the Journal of Neurology Neurosurgery and Psychiatry..."
Source: Deborah Condon. Statins may slow down Alzheimer's. Irish Health (17 November 2005) [FullText]
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