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November 11, 2005

Research ethics in Alzheimer's

"Most people in America approve of allowing patients with Alzheimer's disease to be enrolled in research studies, even when they are not able to provide their own consent, new research has shown.

Ninety per cent of 229 participants in a study carried out by the University of Michigan/University of Rochester in the US said it would be appropriate to allow family members to enroll Alzheimer patients in research that involved mild-to-medium risks, including the testing of new drugs.

A majority of participants in the study also approved of the surrogate decision-making in studies that would involve procedures such as spinal taps, brain tissue sampling and gene transfers.

All the study participants were aged over 70 and at heightened risk of developing Alzheimer's. All had had at least one close blood relative diagnosed with dementia and all were taking part in a study looking at the use of anti-inflammatory drugs to prevent dementia.

Their study authors believe national standards are needed for this type of research issue and that their research may help policy-makers."

Source: Research ethics in Alzheimer's. Irish Health. (9 November 2005) [FullText]

Also see an essay on Alzheimer's corruption by Chris Masterjohn [FullText]

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