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July 13, 2005

Memory Test Predicts Alzheimer's Disease

"Advanced warning of the condition could help people make lifestyle changes to reduce their risk

A word recall test can accurately predict whether someone will develop Alzheimer's disease 10 years later, a Canadian study has shown. The use of this test and similar ones could help people concerned about their risk for the condition, says Dr. Mary Tierney, principal investigator of the study and director of the geriatric research unit at Sunnybrook and Women's College Health Sciences Centre in Toronto. "The majority of people don't get Alzheimer's disease -- the majority of seniors are cognitively intact -- so for many it would be reassurance that the probability of getting Alzheimer's disease was low."

People with worrisome scores might have time to examine and adjust lifestyle factors in an attempt to delay the onset of the disease. Increased mental activity, physical activity and social interaction have all been linked to preventing or delaying Alzheimer's disease. The test results would also give people the opportunity to consider future plans, such as advanced directives and living wills, Tierney says.

She and her colleagues studied 263 seniors who took several mental tests in 1991 and were assessed 10 years later. At that time, 47 were diagnosed with Alzheimer's disease. The results of one test, called the short delayed verbal recall test, predicted which seniors would have a diagnosis of Alzheimer's disease 10 years later. The test involves a tester listing 15 common words, which the participant is asked to repeat five times. A second list is then introduced and the participant is asked to repeat those words, and then the words from the original list.

Source: Memory test predicts Alzheimer's disease. Macleans.ca (13 July 2005) [FullText]

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